High Direct Bilirubin Associated With Levoffoxacin Use in a Neonate
نویسندگان
چکیده
منابع مشابه
Measurement of direct bilirubin by use of bilirubin oxidase.
We developed an enzymatic method for measuring direct-reacting bilirubin (DBIL) in serum. At pH 4.5, bilirubin oxidase (BOX) oxidizes mono-conjugated bilirubin, di-conjugated bilirubin, and most of the delta-bilirubin to biliverdin. The resulting decrease in absorbance at 460 nm is linearly related to the concentration of DBIL in serum. Mean DBIL values in the 51 patients' sera examined by the ...
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The molar absorptivity of unconjugated bilirubin in caffeine reagent is independent of the protein matrix. This finding, together with the simplicity of a dilution step for direct spectrophotometry, will improve the calibration methods of bilirubin and make them more nearly accurate. This is encouraging for the development of a new method for bilirubin determination in neonates; moreover, the c...
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Both total and direct bilirubin measure the formation of azobilirubin, which is detected at 570/660 nm. The total bilirubin reaction contains surfactant and caffeine, which solubilize “indirect” bilirubin and accelerate the reaction (1). Direct bilirubin is a component of total bilirubin and therefore should always be smaller in value. The presence of a monoclonal immunoglobulin (2220mg/dL) fal...
متن کاملInaccurate values for direct bilirubin with some commonly used direct bilirubin procedures.
We compared five methods for the determination of total and direct bilirubins in serum samples from normal controls, subjects with Gilbert's syndrome, and serum pools containing about 50 and 150 mg of total bilirubin per liter. The Kodak Ektachem method and a diazotized sulfanilic acid method with 0.15 mmol/L sodium nitrite concentrations are the only methods that gave accurate direct bilirubin...
متن کاملDirect Phase Imaging in Neonate
Introduction: Direct phase images have been shown to yield superior gray (GM) and white matter (WM) contrast at high field compared to conventional magnitude images [1]; however, the contrast mechanisms are still being discussed. Previous studies are limited to high field and adult volunteers or patients [2]. In this study, phase imaging in neonates is demonstrated for the first time. Since the...
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ژورنال
عنوان ژورنال: The Journal of Pediatric Pharmacology and Therapeutics
سال: 2020
ISSN: 1551-6776
DOI: 10.5863/1551-6776-25.1.64